Clocapramine dihydrochloride hydrate ( —— )

产品货号. M26121 CAS No. 60789-62-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Clocapramine dihydrochloride hydrate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Clocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.
产品描述

Clocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.(In Vivo):Clocapramine shows the lowest potency for D2-occupancy in vivo . An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2 and frontal serotonin-5-HT2 receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50s: 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2) .
同义词

——
通路

Others
靶点

Other Targets
受体

Wnt
研究领域

——
适应症

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1.Charlene F. Barroga, et al. Diketones and hydroxyketones as catenin signaling pathway activators. WO2012024404A1.

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